Oophorectomy improves pituitary activin inhibitory function preventing lactotroph hyperplasia development. Peña-Zanoni M, Faraoni EY, Abeledo-Machado A, Perez PA, Marcial López CA, Camilletti MA, Gutierrez S, Rulli SB, Diaz-Torga G.Endocr Relat Cancer. 2022 May 11;29(6):359-373. doi: 10.1530/ERC-21-0397.PMID: 35324456

Perinatal DEHP exposure modulates pituitary estrogen receptor α and β expression altering lactotroph and somatotroph cell growth in prepuberal and adult male rats. Pérez PA, Toledo J, Picech F, Petiti JP, Mukdsi JH, Diaz-Torga G, Torres AI, De Paul AL, Gutiérrez S.Food Chem Toxicol. 2021 Dec;158:112649. doi: 10.1016/j.fct.2021.112649. Epub 2021 Oct 30.PMID: 34728246

Changes of stem cell niche during experimental pituitary tumor development. Guido CB, Sosa LDV, Perez PA, Zlocoswki N, Velazquez FN, Gutierrez S, Petiti JP, Mukdsi JH, Torres AI.J Neuroendocrinol. 2021 Dec;33(12):e13051. doi: 10.1111/jne.13051. Epub 2021 Oct 27.PMID: 34708474

TGF-β1/Smad2/3 signaling pathway modulates octreotide antisecretory and antiproliferative effects in pituitary somatotroph tumor cells. Picech F, Sosa LD, Perez PA, Cecenarro L, Oms SR, Coca HA, De Battista JC, Gutiérrez S, Mukdsi JH, Torres AI, Petiti JP.J Cell Physiol. 2021 Oct;236(10):6974-6987. doi: 10.1002/jcp.30360. Epub 2021 Mar 8.PMID: 33682941

Association of PTP4A3 expression and tumour size in functioning pituitary adenoma: a descriptive study.

Moyano Crespo GD, Cecenarro LA, Perez P, Guido C, Sosa LDV, Berhard C, Aballay LR, Gutiérrez S, Petiti JP, Torres A, Mukdsi J.J Clin Pathol. 2021 Mar;74(3):190-193. doi: 10.1136/jclinpath-2020-206728. Epub 2020 Jul 2.PMID: 32616539

The phthalate DEHP modulates the estrogen receptors α and β increasing lactotroph cell population in female pituitary glands. Pérez PA, Toledo J, Sosa LDV, Peinetti N, Torres AI, De Paul AL, Gutiérrez S.Chemosphere. 2020 Nov;258:127304. doi: 10.1016/j.chemosphere.2020.127304. Epub 2020 Jun 6.PMID: 32559490

TGFβ1 regulates prolactin secretion during postnatal development: gender differences. Abeledo-Machado A, Pérez PA, Camilletti MA, Faraoni EY, Picech F, Petiti JP, Gutiérrez S, Diaz-Torga G.J Endocrinol. 2020 Jul;246(1):29-39. doi: 10.1530/JOE-20-0041.PMID: 32302971

Pivotal role of NF-κB in cellular senescence of experimental pituitary tumours. Mongi-Bragato B, Grondona E, Sosa LDV, Zlocowski N, Venier AC, Torres AI, Latini A, Leal RB, Gutiérrez S, De Paul AL.J Endocrinol. 2020 May;245(2):179-191. doi: 10.1530/JOE-19-0506.PMID: 32092035

mPRs represent a novel target for PRL inhibition in experimental prolactinomas. Camilletti MA, Abeledo-Machado A, Perez PA, Faraoni EY, De Fino F, Rulli SB, Ferraris J, Pisera D, Gutierrez S, Thomas P, Díaz-Torga G.Endocr Relat Cancer. 2019 May;26(5):497-510. doi: 10.1530/ERC-18-0409.PMID: 30856609

Role of GPER in the anterior pituitary gland focusing on lactotroph function. Camilletti MA, Abeledo-Machado A, Ferraris J, Pérez PA, Faraoni EY, Pisera D, Gutierrez S, Díaz-Torga G.J Endocrinol. 2019 Feb 1;240(2):99-110. doi: 10.1530/JOE-18-0402.PMID: 30400046

The ERα membrane pool modulates the proliferation of pituitary tumours. Sosa LDV, Petiti JP, Picech F, Chumpen S, Nicola JP, Perez P, De Paul A, Valdez-Taubas J, Gutierrez S, Torres AI.J Endocrinol. 2019 Feb 1;240(2):229-241. doi: 10.1530/JOE-18-0418.PMID: 30400032

Trastuzumab inhibits pituitary tumor cell growth modulating the TGFB/SMAD2/3 pathway. Petiti JP, Sosa LDV, Picech F, Moyano Crespo GD, Arevalo Rojas JZ, Pérez PA, Guido CB, Leimgruber C, Sabatino ME, García P, Bengio V, Papalini FR, Estario P, Berhard C, Villarreal M, Gutiérrez S, De Paul AL, Mukdsi JH, Torres AI.Endocr Relat Cancer. 2018 Oct;25(10):837-852. doi: 10.1530/ERC-18-0067. Epub 2018 Jun 6.PMID: 29875136

Oxidative stress and mitochondrial adaptive shift during pituitary tumoral growth. Sabatino ME, Grondona E, Sosa LDV, Mongi Bragato B, Carreño L, Juarez V, da Silva RA, Remor A, de Bortoli L, de Paula Martins R, Pérez PA, Petiti JP, Gutiérrez S, Torres AI, Latini A, De Paul AL.Free Radic Biol Med. 2018 May 20;120:41-55. doi: 10.1016/j.freeradbiomed.2018.03.019. Epub 2018 Mar 13.PMID: 29548793

Estrogen receptor β regulates the tumoral suppressor PTEN to modulate pituitary cell growth. Perez PA, Petiti JP, Picech F, Guido CB, dV Sosa L, Grondona E, Mukdsi JH, De Paul AL, Torres AI, Gutierrez S.J Cell Physiol. 2018 Feb;233(2):1402-1413. doi: 10.1002/jcp.26025. Epub 2017 Jun 15.PMID: 28542730

Oxidative stress and mitochondrial adaptive shift during pituitary tumoral growth.

Sabatino ME, Grondona E, Sosa LDV, Mongi Bragato B, Carreño L, Juarez V, da Silva RA, Remor A, de Bortoli L, de Paula Martins R, Pérez PA, Petiti JP, Gutiérrez S, Torres AI, Latini A, De Paul AL.Free Radic Biol Med. 2018 May 20;120:41-55. doi: 10.1016/j.freeradbiomed.2018.03.019. Epub 2018 Mar 13.PMID: 29548793

Estrogen receptor β regulates the tumoral suppressor PTEN to modulate pituitary cell growth. Perez PA, Petiti JP, Picech F, Guido CB, dV Sosa L, Grondona E, Mukdsi JH, De Paul AL, Torres AI, Gutierrez S.J Cell Physiol. 2018 Feb;233(2):1402-1413. doi: 10.1002/jcp.26025. Epub 2017 Jun 15.PMID: 28542730

Inhibitory role of ERβ on anterior pituitary cell proliferation by controlling the expression of proteins related to cell cycle progression. Pérez PA, Petiti JP, Wagner IA, Sabatino ME, Sasso CV, De Paul AL, Torres AI, Gutiérrez S.Mol Cell Endocrinol. 2015 Nov 5;415:100-13. doi: 10.1016/j.mce.2015.08.009. Epub 2015 Aug 14.PMID: 26282612